ID   iVMP C1
AC   CVCL_F0D2
SY   immortalized VM Precursor clone C1; C1
RX   PubMed=20177706;
RX   PubMed=22863662;
CC   Doubling time: 18.3 hours (PubMed=20177706).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen (Note=With p.Leu156_Thr708del = T155g).
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pSV3-neo).
CC   Derived from site: In situ; Embryonic brain, ventral mesencephalon; UBERON=UBERON_0001943.
CC   Cell type: Neural progenitor cell; CL=CL_0011020.
CC   Breed/subspecies: Sprague Dawley; RS=RS_0000681.
OX   NCBI_TaxID=10116; ! Rattus norvegicus (Rat)
OI   CVCL_F0D3 ! iVMP C2
OI   CVCL_F0D4 ! iVMP C3
OI   CVCL_F0D5 ! iVMP C4
SX   Sex unspecified
AG   12FD
CA   Transformed cell line
DT   Created: 14-08-25; Last updated: 14-08-25; Version: 1
//
RX   PubMed=20177706; DOI=10.1007/s00441-010-0933-4;
RA   Nobre, Andre
RA   Kalve, Ieva
RA   Cesnulevicius, Konstantin
RA   Ragancokova, Daniela
RA   Ratzka, Andreas
RA   Halfer, Nina
RA   Wesemann, Maike
RA   Krampfl, Klaus
RA   Claus, Peter
RA   Grothe, Claudia
RT   "Characterization and differentiation potential of rat ventral
RT   mesencephalic neuronal progenitor cells immortalized with SV40 large
RT   T antigen.";
RL   Cell Tissue Res. 340:29-43(2010).
//
RX   PubMed=22863662; DOI=10.1111/j.1582-4934.2012.01607.x; PMCID=PMC4118228;
RA   Alwin Prem Anand, Asir
RA   Sankar, S. Gowri
RA   Vani, Kokila V.
RT   "Immortalization of neuronal progenitors using SV40 large T antigen
RT   and differentiation towards dopaminergic neurons.";
RL   J. Cell. Mol. Med. 16:2592-2610(2012).
//