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Cellosaurus HL-60 neutrophilic subline No. 14 (CVCL_F0CU)

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Cell line name HL-60 neutrophilic subline No. 14
Accession CVCL_F0CU
Resource Identification Initiative To cite this cell line use: HL-60 neutrophilic subline No. 14 (RRID:CVCL_F0CU)
Comments Population: Caucasian.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Gene deletion; HGNC; HGNC:11998; TP53; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Arg80Ter (c.238C>T) (p.Pro94Leu, c.281C>T); ClinVar=VCV000009409; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
Disease Adult acute myeloid leukemia with maturation (NCIt: C7961)
Acute myeloblastic leukemia with maturation (ORDO: Orphanet_98834)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0002 (HL-60)
Sex of cell Female
Age at sampling 36Y
Category Cancer cell line
Publications

PubMed=3486011; DOI=10.1182/blood.V67.5.1433.1433
Masao Tomonaga, Judith C. Gasson, Shirley G. Quan, David W. Golde;
Establishment of eosinophilic sublines from human promyelocytic leukemia (HL-60) cells: demonstration of multipotentiality and single-lineage commitment of HL-60 stem cells.
Blood 67:1433-1441(1986)

Entry history
Entry creation14-Aug-2025
Last entry update14-Aug-2025
Version number1