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Cellosaurus HBEC3KT53 (CVCL_EQ78)

[Text version]
Cell line name HBEC3KT53
Synonyms HBEC 3KT53
Accession CVCL_EQ78
Resource Identification Initiative To cite this cell line use: HBEC3KT53 (RRID:CVCL_EQ78)
Comments Knockout cell: Method=siRNA knockdown; HGNC; HGNC:11998; TP53.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=MGI; MGI:88357; Cdk4.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: In situ; Lung, bronchus, epithelium; UBERON=UBERON_0002031.
Cell type: Epithelial cell of bronchus; CL=CL_0002328.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_X491 (HBEC3-KT)
Children:
CVCL_EQ79 (HBEC3KTRL53)
Sex of cell Female
Age at sampling 65Y
Category Telomerase immortalized cell line
Publications

PubMed=24240690; DOI=10.1038/onc.2013.486; PMCID=PMC4025984
Elma Zaganjor, Jihan K. Osborne, Lauren M. Weil, Laura A. Diaz-Martinez, Joshua X. Gonzales, Stina M. Singel, Jill E. Larsen, Luc Girard, John D. Minna, Melanie H. Cobb;
Ras regulates kinesin 13 family members to control cell migration pathways in transformed human bronchial epithelial cells.
Oncogene 33:5457-5466(2014)

Cross-references
Encyclopedic resources Wikidata; Q54881415
Entry history
Entry creation26-Sep-2016
Last entry update14-Aug-2025
Version number17