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Cellosaurus SKBR3-PR (CVCL_EQ69)

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Cell line name SKBR3-PR
Synonyms SKBR3 PR
Accession CVCL_EQ69
Resource Identification Initiative To cite this cell line use: SKBR3-PR (RRID:CVCL_EQ69)
Comments Population: Caucasian.
Knockout cell: Method=shRNA knockdown; HGNC; HGNC:9588; PTEN.
Omics: Transcriptomics; Microarray.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene deletion; HGNC; HGNC:1748; CDH1; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg175His (c.524G>A); ClinVar=VCV000012374; Zygosity=Homozygous (from parent cell line).
Disease Breast adenocarcinoma (NCIt: C5214)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0033 (SK-BR-3)
Sex of cell Female
Age at sampling 43Y
Category Cancer cell line
Publications

PubMed=17560336; DOI=10.1016/j.ccr.2007.04.021
Igor Vivanco, Nicolaos Palaskas, Chris Tran, Stephen P. Finn, Gad Getz, Norman J. Kennedy, Jing Jiao, Joshua Rose, Wan-Ling Xie, Massimo Loda, Todd Robert Golub ...Show all 15 authors... , Ingo K. Mellinghoff, Roger John Davis, Hong Wu, Charles Lazelle Sawyers; Show fewer authors
Identification of the JNK signaling pathway as a functional target of the tumor suppressor PTEN.
Cancer Cell 11:555-569(2007)

Cross-references
Cell line databases/resources cancercelllines; CVCL_EQ69
Encyclopedic resources Wikidata; Q54954676
Gene expression databases GEO; GSM183442
GEO; GSM183443
Entry history
Entry creation26-Sep-2016
Last entry update10-Apr-2025
Version number12