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Cellosaurus Hep-G2/BGAL (CVCL_EQ66)

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Cell line name Hep-G2/BGAL
Accession CVCL_EQ66
Resource Identification Initiative To cite this cell line use: Hep-G2/BGAL (RRID:CVCL_EQ66)
Comments Population: Caucasian.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00722; Escherichia coli beta-galactosidase (lacZ).
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Disease Hepatoblastoma (NCIt: C3728)
Hepatoblastoma (ORDO: Orphanet_449)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0027 (Hep-G2)
Sex of cell Male
Age at sampling 15Y
Category Cancer cell line
Publications

PubMed=17157261; DOI=10.1016/j.molcel.2006.10.012
Stephanie Gaillard, Linda L. Grasfeder, Christiane L. Haeffele, Edward K. Lobenhofer, Tzu-Ming Chu, Russ Wolfinger, Dmitri Kazmin, Timothy Robert Koves, Deborah M. Muoio, Ching-Yi Chang, Donald Patrick McDonnell;
Receptor-selective coactivators as tools to define the biology of specific receptor-coactivator pairs.
Mol. Cell 24:797-803(2006)

Cross-references
Cell line databases/resources cancercelllines; CVCL_EQ66
Encyclopedic resources Wikidata; Q54882788
Gene expression databases GEO; GSM138625
GEO; GSM138626
GEO; GSM138627
Entry history
Entry creation26-Sep-2016
Last entry update10-Apr-2025
Version number17