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Cellosaurus ER-SQ20B (CVCL_EI29)

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Cell line name ER-SQ20B
Accession CVCL_EI29
Resource Identification Initiative To cite this cell line use: ER-SQ20B (RRID:CVCL_EI29)
Comments Selected for resistance to: ChEBI; CHEBI_114785; Erlotinib.
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Larynx; UBERON=UBERON_0001737.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; c.376-1G>A (p.Tyr126_Lys132del, c.376_396del21); ClinVar=VCV000481003; Zygosity=Unspecified; Note=Splice acceptor mutation (from parent cell line).
Disease Laryngeal squamous cell carcinoma (NCIt: C4044)
Squamous cell carcinoma of the larynx (ORDO: Orphanet_494550)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_7138 (SQ-20B)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=25888065; DOI=10.1016/j.molonc.2015.03.008; PMCID=PMC4523436
Aditya Stanam, Laurie Love-Homan, Tisha S. Joseph, Madelyn Espinosa-Cotton, Andrean L. Simons;
Upregulated interleukin-6 expression contributes to erlotinib resistance in head and neck squamous cell carcinoma.
Mol. Oncol. 9:1371-1383(2015)

Cross-references
Cell line databases/resources cancercelllines; CVCL_EI29
Encyclopedic resources Wikidata; Q54832420
Gene expression databases GEO; GSM1524319
GEO; GSM1524320
GEO; GSM1524321
Entry history
Entry creation26-Sep-2016
Last entry update10-Apr-2025
Version number11