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Cellosaurus FaDu/T (CVCL_EG58)

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Cell line name FaDu/T
Synonyms FaDu/T-200
Accession CVCL_EG58
Resource Identification Initiative To cite this cell line use: FaDu/T (RRID:CVCL_EG58)
Comments Population: Indian.
Selected for resistance to: ChEBI; CHEBI_45863; Paclitaxel (Taxol).
Derived from site: In situ; Pharynx, hypopharynx; UBERON=UBERON_0001051.
Cell type: Epithelial cell; CL=CL_0000066.
Sequence variations
  • Mutation; HGNC; HGNC:1787; CDKN2A; Simple; c.151-1G>T; ClinVar=VCV000422058; Zygosity=Homozygous; Note=Splice acceptor mutation (from parent cell line).
  • Mutation; HGNC; HGNC:3595; FAT1; Simple; p.Lys3277Asnfs*4 (c.9828delG) (p.Gly3276fs); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; c.376-1G>A (p.Tyr126_Lys132del, c.376_396del21); ClinVar=VCV000481003; Zygosity=Heterozygous; Note=Splice acceptor mutation (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Leu (c.743G>T); ClinVar=VCV000230253; Zygosity=Heterozygous (from parent cell line).
Disease Hypopharyngeal squamous cell carcinoma (NCIt: C4043)
Squamous cell carcinoma of the hypopharynx (ORDO: Orphanet_494547)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1218 (FaDu)
Sex of cell Male
Age at sampling 56Y
Category Cancer cell line
Publications

PubMed=21833476; DOI=10.3892/or.2011.1418
Ju-Ke Ma, Su-Mei Lu, Liang Yu, Jia-Jun Tian, Jian-Feng Li, Hai-Bo Wang, Wei Xu;
FaDu cell characteristics induced by multidrug resistance.
Oncol. Rep. 26:1189-1195(2011)

Cross-references
Cell line databases/resources cancercelllines; CVCL_EG58
Encyclopedic resources Wikidata; Q54833223
Entry history
Entry creation13-Jul-2016
Last entry update14-Aug-2025
Version number16