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Cellosaurus KTR6 (CVCL_E9WI)

[Text version]
Cell line name KTR6
Accession CVCL_E9WI
Resource Identification Initiative To cite this cell line use: KTR6 (RRID:CVCL_E9WI)
Comments Population: Japanese.
Selected for resistance to: ChEBI; CHEBI_45783; Imatinib (Gleevec; STI571).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1014; BCR; Name(s)=BCR-ABL1, BCR-ABL (from parent cell line).
Disease Chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C3174)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_D200 (KT-1 [Human leukemia])
Sex of cell Male
Age at sampling 32Y
Category Cancer cell line
Publications

PubMed=12842705; DOI=10.1016/s0301-472x(03)00089-4
Takatsune Shimizu, Yoshitaka Miyakawa, Atsushi Oda, Masahiro Kizaki, Yasuo Ikeda;
STI571-resistant KT-1 cells are sensitive to interferon-alpha accompanied by the loss of T-cell protein tyrosine phosphatase and prolonged phosphorylation of Stat1.
Exp. Hematol. 31:601-608(2003)

Entry history
Entry creation14-Aug-2025
Last entry update14-Aug-2025
Version number1