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Cellosaurus 661W-A11 (CVCL_E9DQ)

[Text version]
Cell line name 661W-A11
Accession CVCL_E9DQ
Resource Identification Initiative To cite this cell line use: 661W-A11 (RRID:CVCL_E9DQ)
Comments Characteristics: Shows a significant increase in expression of rod-specific genes but not of cone-specific genes, compared with the parent cell line (PubMed=34208617).
Genetic integration: Method=Transduction; Gene=MGI; MGI:102567; Nrl.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen (Note=Under the control of the IRBP promoter).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Eye, retina; UBERON=UBERON_0000966.
Cell type: Retinal cone cell; CL=CL_0000573.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6N transgenic.
Hierarchy Parent: CVCL_6240 (661W)
Sex of cell Male
Age at sampling Age unspecified
Category Transformed cell line
Publications

PubMed=34208617; DOI=10.3390/ijms22126440; PMCID=PMC8235468
Li Huang, Meltem Kutluer, Elisa Adani, Antonella Comitato, Valeria Marigo;
New in vitro cellular model for molecular studies of retinitis pigmentosa.
Int. J. Mol. Sci. 22:6440.1-6440.12(2021)

Entry history
Entry creation14-Aug-2025
Last entry update14-Aug-2025
Version number1