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Cellosaurus C3H10T1/2 Ras clone C4 (CVCL_E9D8)

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Cell line name C3H10T1/2 Ras clone C4
Synonyms RasC4
Accession CVCL_E9D8
Resource Identification Initiative To cite this cell line use: C3H10T1/2 Ras clone C4 (RRID:CVCL_E9D8)
Comments Genetic integration: Method=Transfection; Gene=HGNC; HGNC:5173; HRAS (Note=With p.Gly12Val).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Derived from site: In situ; Whole embryo; UBERON=UBERON_0000922.
Cell type: Fibroblast; CL=CL_0000057.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C3H.
Hierarchy Parent: CVCL_0190 (C3H/10T1/2 clone 8)
Sex of cell Sex unspecified
Age at sampling Embryo
Category Spontaneously immortalized cell line
Publications

PubMed=3475570; DOI=10.1128/mcb.7.7.2649-2652.1987; PMCID=PMC365407
Edward B. Leof, Jacqueline A. Proper, Harold L. Moses;
Modulation of transforming growth factor type beta action by activated ras and c-myc.
Mol. Cell. Biol. 7:2649-2652(1987)

PubMed=8564977
Claudia J. Morgan, Frank L. Merrill, Ronald W. Trewyn;
Defective transfer RNA-queuine modification in C3H10T1/2 murine fibroblasts transfected with oncogenic ras.
Cancer Res. 56:594-598(1996)

Entry history
Entry creation14-Aug-2025
Last entry update14-Aug-2025
Version number1