Cellosaurus logo
expasy logo

Cellosaurus EC-Gpr21tm1Dgen (CVCL_E9CX)

[Text version]
Cell line name EC-Gpr21tm1Dgen
Synonyms Gpr21 KO ES
Accession CVCL_E9CX
Resource Identification Initiative To cite this cell line use: EC-Gpr21tm1Dgen (RRID:CVCL_E9CX)
Comments Part of: Deltagen knockout ES cell lines.
Characteristics: A IRES-LacZ-Neo cassette is inserted in the targeted gene region.
Knockout cell: Method=Homologous recombination; MGI; MGI:2441890; Gpr21.
Genetic integration: Method=Homologous recombination; Gene=UniProtKB; P00722; Escherichia coli beta-galactosidase (lacZ).
Genetic integration: Method=Homologous recombination; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: 129P2/Ola.
Hierarchy Parent: CVCL_C320 (ES-E14)
Sex of cell Male
Age at sampling Blastocyst stage
Category Embryonic stem cell
Publications

PubMed=22653059; DOI=10.1172/JCI61953; PMCID=PMC3386820
Olivia Osborn, Da Young Oh, Joanne McNelis, Manuel Sanchez-Alavez, Saswata Talukdar, Min Lu, Ping-Ping Li, Lucinda Thiede, Hidetaka Morinaga, Jane J. Kim, Jan Heinrichsdorff ...Show all 18 authors... , Sarah Nalbandian, Jachelle Ofrecio Pimentel, Miriam Scadeng, Simon Schenk, John R. Hadcock, Tamas Bartfai, Jerrold M. Olefsky; Show fewer authors
G protein-coupled receptor 21 deletion improves insulin sensitivity in diet-induced obese mice.
J. Clin. Invest. 122:2444-2453(2012)

Entry history
Entry creation14-Aug-2025
Last entry update14-Aug-2025
Version number1