Cellosaurus cell line Panc1-F-RFP (CVCL

Cellosaurus Panc1-F-RFP (CVCL_E9C3)

Entry history
Cell line name	Panc1-F-RFP
Synonyms	Panc1-RFP
Accession	CVCL_E9C3
Resource Identification Initiative	To cite this cell line use: Panc1-F-RFP (RRID:CVCL_E9C3)
Comments	Population: Caucasian. Characteristics: Expresses farnesylated RFP (PubMed=26999607). Genetic integration: Method=Transfection/transduction; Gene=FPbase; EGE3L; DsRed (Note=drFP583, red fluorescent protein from Discosoma sp.). Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Sequence variations	Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Homozygous (from parent cell line).
Disease	Pancreatic ductal adenocarcinoma (NCIt: C9120)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0480 (PANC-1)
Sex of cell	Male
Age at sampling	56Y
Category	Cancer cell line
Publications	PubMed=26999607; DOI=10.1172/JCI82658; PMCID=PMC4811155 Sylvie Deborde, Tatiana Omelchenko, Anna Lyubchik, Yi Zhou, Shi-Zhi He, William Francis McNamara, Natalya Chernichenko, Sei-Young Lee, Fernando Barajas, Chun-Hao Chen, Richard L. Bakst ...Show all 15 authors... , Efsevia Vakiani, Shuang-Ba He, Alan Hall, Richard J. Wong; Show fewer authors Schwann cells induce cancer cell dispersion and invasion. J. Clin. Invest. 126:1538-1554(2016) PubMed=35881881; DOI=10.1158/2159-8290.CD-21-1690; PMCID=PMC9533012 Sylvie Deborde, Laxmi Gusain, Ann Powers, Andrea R. Marcadis, Ya-Song Yu, Chun-Hao Chen, Anna Frants, Elizabeth Kao, Laura H. Tang, Efsevia Vakiani, Masataka Amisaki ...Show all 17 authors... , Vinod P. Balachandran, Annalisa Calo, Tatiana Omelchenko, Kristjan R. Jessen, Boris A. Reva, Richard J. Wong; Show fewer authors Reprogrammed Schwann cells organize into dynamic tracks that promote pancreatic cancer invasion. Cancer Discov. 12:2454-2473(2022)
Entry creation	14-Aug-2025
Last entry update	14-Aug-2025
Version number	1