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Cellosaurus ICLU-T (CVCL_E8UC)

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Cell line name ICLU-T
Accession CVCL_E8UC
Resource Identification Initiative To cite this cell line use: ICLU-T (RRID:CVCL_E8UC)
Comments Group: Hybridoma fusion partner cell line.
Group: Serum/protein free medium cell line.
Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_63486; 8-azaguanine.
Selected for resistance to: ChEBI; CHEBI_9555; Tioguanine (6-thioguanine; 6-TG).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: T-cell; CL=CL_0000084.
Sequence variations
  • Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:8064; NUP214; Name(s)=NUP214-ABL1; Note=NUP214 exon 34 fused to ABL1 exon 2 (from parent cell line).
  • Mutation; HGNC; HGNC:7881; NOTCH1; Simple; p.Leu1600Pro (c.4799T>C); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr163Cys (c.488A>G); ClinVar=VCV000127814; Zygosity=Heterozygous (from parent cell line).
Disease Childhood T acute lymphoblastic leukemia (NCIt: C7953)
Precursor T-cell acute lymphoblastic leukemia (ORDO: Orphanet_99861)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1913 (Peer)
Sex of cell Female
Age at sampling 4Y
Category Cancer cell line
Publications

PubMed=10405829; DOI=10.3233/HAB-1999-9202
Hiroharu Kawahara, Mari Maeda-Yamamoto, Makiko Suzuki, Katsuhiro Hakamata;
New human fusion partners, ICLU-B, -T, -E for making human hybridomas derived from various immunological cells.
Hum. Antibodies 9:89-94(1999)

Entry history
Entry creation14-Aug-2025
Last entry update14-Aug-2025
Version number1