Cellosaurus cell line Raji 6-TGR-neoR (CVCL

Cellosaurus Raji 6-TGR-neoR (CVCL_E8U5)

[Text version]

Cell line name

Raji 6-TGR-neoR

Accession

CVCL_E8U5

Resource Identification Initiative

To cite this cell line use: Raji 6-TGR-neoR (RRID:CVCL_E8U5)

Comments

Group: Hybridoma fusion partner cell line.
Population: African; Nigerian.
Selected for resistance to: ChEBI; CHEBI_9555; Tioguanine (6-thioguanine; 6-TG).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
Derived from site: In situ; Bone, jaw, maxilla; UBERON=UBERON_0002397.
Cell type: B-cell; CL=CL_0000236.

Sequence variations

Gene fusion; HGNC; HGNC:5477; IGH + HGNC; HGNC:7553; MYC; Name(s)=MYC-IGH (from parent cell line).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg213Gln (c.638G>A); ClinVar=VCV000135359; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr234His (c.700T>C); ClinVar=VCV000376691; Zygosity=Heterozygous (from parent cell line).

Disease

EBV-related Burkitt lymphoma (NCIt: C27694)
Burkitt lymphoma (ORDO: Orphanet_543)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Parent: CVCL_Y035 (Raji 6-TGR)
Children:

CVCL_E8U6 (HYNI-1)

CVCL_E8U7 (HYNI-2)

Sex of cell

Male

Age at sampling

11Y