ID   Raji 6-TGR-neoR
AC   CVCL_E8U5
RX   DOI=10.2177/jsci.11.346;
RX   PubMed=2273757;
RX   PubMed=3267026;
CC   Group: Hybridoma fusion partner cell line.
CC   Population: African; Nigerian.
CC   Selected for resistance to: ChEBI; CHEBI_9555; Tioguanine (6-thioguanine; 6-TG).
CC   Sequence variation: Gene fusion; HGNC; HGNC:5477; IGH + HGNC; HGNC:7553; MYC; Name(s)=MYC-IGH (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg213Gln (c.638G>A); ClinVar=VCV000135359; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr234His (c.700T>C); ClinVar=VCV000376691; Zygosity=Heterozygous (from parent cell line).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
CC   Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
CC   Derived from site: In situ; Bone, jaw, maxilla; UBERON=UBERON_0002397.
CC   Cell type: B-cell; CL=CL_0000236.
DI   NCIt; C27694; EBV-related Burkitt lymphoma
DI   ORDO; Orphanet_543; Burkitt lymphoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_Y035 ! Raji 6-TGR
SX   Male
AG   11Y
CA   Cancer cell line
DT   Created: 14-08-25; Last updated: 14-08-25; Version: 1
//
RX   DOI=10.2177/jsci.11.346;
RA   Ikewaki, Nobunao
RT   "Establishment of a 6-thioguanine (6-TG)-neo-resistant mutant human
RT   lymphoma cell line.";
RL   Jpn. J. Clin. Immunol. 11:346-356(1988).
//
RX   PubMed=2273757;
RA   Ikewaki, Nobunao
RT   "Differentiation of a human B cell hybridoma with interleukin-2
RT   receptor.";
RL   Kitasato Arch. Exp. Med. 63:31-36(1990).
//
RX   PubMed=3267026;
RA   Ikewaki, Nobunao
RT   "Production of human B cell hybridomas with interleukin 2 receptors
RT   selected by a new selective medium, HAT-neo.";
RL   Kitasato Arch. Exp. Med. 61:225-235(1988).
//