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Cellosaurus MP41/RFP (CVCL_E8SZ)

[Text version]
Cell line name MP41/RFP
Synonyms MP41 / RFP
Accession CVCL_E8SZ
Resource Identification Initiative To cite this cell line use: MP41/RFP (RRID:CVCL_E8SZ)
Comments Characteristics: Transduced by lentivirus with a EF1a-RFP-Rsv-PuroR construct (GenTarget=SC089-R).
Genetic integration: Method=Transduction; Gene=FPbase; EGE3L; DsRed (Note=drFP583, red fluorescent protein from Discosoma sp.).
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: In situ; Eye, uvea; UBERON=UBERON_0001768.
Cell type: Epithelial cell; CL=CL_0000066.
Sequence variations
  • Mutation; HGNC; HGNC:4379; GNA11; Simple; p.Gln209Leu (c.626A>T); ClinVar=VCV000376002; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11100; SMARCA4; Simple; p.Thr910Met (c.2729C>T); ClinVar=VCV000438790; Zygosity=Heterozygous (from parent cell line).
Disease Uveal melanoma (NCIt: C7712)
Uveal melanoma (ORDO: Orphanet_39044)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_4D12 (MP41)
Sex of cell Female
Age at sampling 49Y
Category Cancer cell line
Web pages Provider; GenTarget; SC089-R; https://www.gentarget.com/product/human-mp41-rfp-fluorescent-stable-cells/
Entry history
Entry creation14-Aug-2025
Last entry update14-Aug-2025
Version number1