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Cellosaurus HT1080 human FAP (CVCL_E8JG)

[Text version]
Cell line name HT1080 human FAP
Synonyms HT1080-FAP
Accession CVCL_E8JG
Resource Identification Initiative To cite this cell line use: HT1080 human FAP (RRID:CVCL_E8JG)
Comments Population: Caucasian.
Doubling time: ~48 hours (KYinno=KC-2635).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:3590; FAP.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: In situ; Bone, pelvis, acetabulum; UBERON=UBERON_0001269.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:5382; IDH1; Simple; p.Arg132Cys (c.394C>T); ClinVar=VCV000375891; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (from parent cell line).
Disease Fibrosarcoma (NCIt: C3043)
Fibrosarcoma (ORDO: Orphanet_2030)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0317 (HT-1080)
Sex of cell Male
Age at sampling 35Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) KYinno; KC-2635
Entry history
Entry creation14-Aug-2025
Last entry update14-Aug-2025
Version number1