Cellosaurus cell line BxPC-3 human GPRC5D (CVCL

Cross-references
Cell line name	BxPC-3 human GPRC5D
Synonyms	BxPC3-GPRC5D
Accession	CVCL_E8JD
Resource Identification Initiative	To cite this cell line use: BxPC-3 human GPRC5D (RRID:CVCL_E8JD)
Comments	Population: Caucasian. Genetic integration: Method=Transduction; Gene=HGNC; HGNC:13310; GPRC5D. Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR). Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Sequence variations	Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line). Gene deletion; HGNC; HGNC:6770; SMAD4; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val487_Pro492delinsAla (c.1460_1474delGTGTAGGTGCTGTCA); Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:6407; KRAS; None_reported; -; Zygosity=- (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr220Cys (c.659A>G); ClinVar=VCV000127819; Zygosity=Homozygous (from parent cell line).
Disease	Pancreatic ductal adenocarcinoma (NCIt: C9120)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0186 (BxPC-3)
Sex of cell	Female
Age at sampling	61Y
Category	Cancer cell line
Cell line collections (Providers)	KYinno; KC-1717
Entry history
Entry creation	14-Aug-2025
Last entry update	14-Aug-2025
Version number	1