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Cellosaurus TMD8-BTK-T474I-KI-1A1 (CVCL_E8J7)

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Cell line name TMD8-BTK-T474I-KI-1A1
Accession CVCL_E8J7
Resource Identification Initiative To cite this cell line use: TMD8-BTK-T474I-KI-1A1 (RRID:CVCL_E8J7)
Comments Population: Japanese.
Doubling time: ~30 hours (KYinno=KC-4715).
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Sequence variations
  • Mutation; HGNC; HGNC:1133; BTK; Simple_edited; p.Thr474Ile (c.1421C>T); Zygosity=Hemizygous (KYinno=KC-4715).
  • Mutation; HGNC; HGNC:1699; CD79B; Simple; p.Tyr196His (c.586T>C); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:7562; MYD88; Simple; p.Leu252Pro (c.755T>C) (p.Leu265Pro, c.794T>C) (L265P); ClinVar=VCV000037055; Zygosity=Heterozygous (from parent cell line).
Disease Diffuse large B-cell lymphoma activated B-cell type (NCIt: C36081)
Diffuse large B-cell lymphoma (ORDO: Orphanet_544)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_A442 (TMD8)
Sex of cell Male
Age at sampling 62Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) KYinno; KC-4715
Entry history
Entry creation14-Aug-2025
Last entry update14-Aug-2025
Version number1