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Cellosaurus ENKL-J1 (CVCL_E8FI)

[Text version]
Cell line name ENKL-J1
Accession CVCL_E8FI
Resource Identification Initiative To cite this cell line use: ENKL-J1 (RRID:CVCL_E8FI)
Comments Population: Japanese.
Characteristics: Eprenetapopt, tazemetostat and vorinostat efficiently induced apoptosis in this cell line (PubMed=38029851).
Doubling time: 80.6 hours (Note=In normoxic culture conditions), 66.46 hours (Note=In hypoxic culture conditions, 1% O2) (PubMed=38029851).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Omics: Transcriptomics; RNAseq; Single cell.
Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371.
Cell type: NK T-cell; CL=CL_0000814.
Sequence variations
  • Mutation; HGNC; HGNC:25941; TET2; Simple; p.Pro29Arg (c.86C>G); ClinVar= VCV000135316; Zygosity=Heterozygous (PubMed=38029851).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg280Lys (c.839G>A); ClinVar=VCV000376657; Zygosity=Homozygous (PubMed=38029851).
Disease Nasal type extranodal NK/T-cell lymphoma (NCIt: C4684)
Extranodal nasal NK/T cell lymphoma (ORDO: Orphanet_86879)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 29Y
Category Cancer cell line
Publications

PubMed=38029851; DOI=10.1016/j.exphem.2023.11.006
Sato S., Ishii M., Tachibana K., Furukawa Y., Toyota T., Kinoshita S., Azusawa Y., Ando J., Ando M.
Establishment of ganglioside GD2-expressing extranodal NK/T-cell lymphoma cell line with scRNA-seq analysis.
Exp. Hematol. 130:104132.1-104132.12(2024)

Cross-references
Gene expression databases GEO; GSM7985990
Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1