ID   ENKL-J1
AC   CVCL_E8FI
DR   GEO; GSM7985990
RX   PubMed=38029851;
CC   Population: Japanese.
CC   Characteristics: Eprenetapopt, tazemetostat and vorinostat efficiently induced apoptosis in this cell line (PubMed=38029851).
CC   Doubling time: 80.6 hours (Note=In normoxic culture conditions), 66.46 hours (Note=In hypoxic culture conditions, 1% O2) (PubMed=38029851).
CC   Sequence variation: Mutation; HGNC; HGNC:25941; TET2; Simple; p.Pro29Arg (c.86C>G); ClinVar= VCV000135316; Zygosity=Heterozygous (PubMed=38029851).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg280Lys (c.839G>A); ClinVar=VCV000376657; Zygosity=Homozygous (PubMed=38029851).
CC   Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
CC   Omics: Transcriptomics; RNAseq; Single cell.
CC   Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371.
CC   Cell type: NK T-cell; CL=CL_0000814.
DI   NCIt; C4684; Nasal type extranodal NK/T-cell lymphoma
DI   ORDO; Orphanet_86879; Extranodal nasal NK/T cell lymphoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   29Y
CA   Cancer cell line
DT   Created: 10-04-25; Last updated: 10-04-25; Version: 1
//
RX   PubMed=38029851; DOI=10.1016/j.exphem.2023.11.006;
RA   Sato S., Ishii M., Tachibana K., Furukawa Y., Toyota T., Kinoshita S.,
RA   Azusawa Y., Ando J., Ando M.;
RT   "Establishment of ganglioside GD2-expressing extranodal NK/T-cell
RT   lymphoma cell line with scRNA-seq analysis.";
RL   Exp. Hematol. 130:104132.1-104132.12(2024).
//