Cellosaurus HT1080-HMGB1-Lucia (CVCL_E8F2)
Cell line name | HT1080-HMGB1-Lucia |
---|---|
Accession | CVCL_E8F2 |
Resource Identification Initiative | To cite this cell line use: HT1080-HMGB1-Lucia (RRID:CVCL_E8F2) |
Comments | Population: Caucasian. Characteristics: Designed to monitor ferroptosis, a form of non-apoptotic cell death. Stably express an HMGB1::Lucia luciferase fusion protein in the cytoplasm, following ferroptosis activation, the cell membrane ruptures and HMGB1::Lucia is released in the extracellular milieu (InvivoGen=ht80-gb1lc). Genetic integration: Method=Transfection; Gene=HGNC; HGNC:4983; HMGB1. Genetic integration: Method=Transfection; Gene=UniProtKB; P33967; B.cereus Bsr. Genetic integration: Method=Transfection; Gene=Lucia luciferase (Note=Synthetic gene designed on natural secreted luciferase genes from marine copepods). Derived from site: In situ; Bone, pelvis, acetabulum; UBERON=UBERON_0001269. |
Sequence variations |
|
Disease | Fibrosarcoma (NCIt: C3043) Fibrosarcoma (ORDO: Orphanet_2030) |
Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
Hierarchy | Parent: CVCL_0317 (HT-1080) |
Sex of cell | Male |
Age at sampling | 35Y |
Category | Cancer cell line |
Cross-references | |
Cell line collections (Providers) | InvivoGen; ht80-gb1lc |
Entry history | |
Entry creation | 10-Apr-2025 |
Last entry update | 10-Apr-2025 |
Version number | 1 |