Cellosaurus cell line BPS Bioscience Raji CD19 KO (CVCL

Entry history
Cell line name	BPS Bioscience Raji CD19 KO
Synonyms	CD19 knockout Raji
Accession	CVCL_E8DN
Resource Identification Initiative	To cite this cell line use: BPS Bioscience Raji CD19 KO (RRID:CVCL_E8DN)
Comments	Population: African; Nigerian. Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:1633; CD19. Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV). Derived from site: In situ; Bone, jaw, maxilla; UBERON=UBERON_0002397. Cell type: B-cell; CL=CL_0000236.
Sequence variations	Gene fusion; HGNC; HGNC:5477; IGH + HGNC; HGNC:7553; MYC; Name(s)=MYC-IGH (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg213Gln (c.638G>A); ClinVar=VCV000135359; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr234His (c.700T>C); ClinVar=VCV000376691; Zygosity=Heterozygous (from parent cell line).
Disease	EBV-related Burkitt lymphoma (NCIt: C27694) Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0511 (Raji)
Sex of cell	Male
Age at sampling	11Y
Category	Cancer cell line
Web pages	Provider; BPS Bioscience; 82166; https://bpsbioscience.com/cd19-knockout-raji-cell-line-82166
Entry creation	10-Apr-2025
Last entry update	10-Apr-2025
Version number	1