Cellosaurus HeLa-H12 (CVCL_E8AQ)
| Cell line name | HeLa-H12 |
|---|---|
| Synonyms | HeLa-LTR-lacZ clone Z24 CD4 clone H12 |
| Accession | CVCL_E8AQ |
| Resource Identification Initiative | To cite this cell line use: HeLa-H12 (RRID:CVCL_E8AQ) |
| Comments | Population: African American. Characteristics: Expression of CD4 is under the control of a SV40 promoter (PubMed=1560526). Characteristics: Transfected with a construct pMA175 containing the HIV-1 BRU LTR that allows expression of lacZ when Tat is present (from parent cell line). Genetic integration: Method=Transfection; Gene=HGNC; HGNC:1678; CD4. Genetic integration: Method=Transfection; Gene=UniProtKB; P00722; Escherichia coli beta-galactosidase (lacZ). Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR). Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo. Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18). Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002. |
| Disease | Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677) |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_E8AP (HeLa-LTR-lacZ clone Z24) |
| Sex of cell | Female |
| Age at sampling | 30Y6M |
| Category | Cancer cell line |
| Publications | PubMed=1560526; DOI=10.1128/JVI.66.5.2814-2820.1992; PMCID=PMC241038 |
| Entry history | |
| Entry creation | 10-Apr-2025 |
| Last entry update | 10-Apr-2025 |
| Version number | 1 |