ID   HeLa-H12
AC   CVCL_E8AQ
SY   HeLa-LTR-lacZ clone Z24 CD4 clone H12
RX   PubMed=1560526;
CC   Population: African American.
CC   Characteristics: Expression of CD4 is under the control of a SV40 promoter (PubMed=1560526).
CC   Characteristics: Transfected with a construct pMA175 containing the HIV-1 BRU LTR that allows expression of lacZ when Tat is present (from parent cell line).
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:1678; CD4.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00722; Escherichia coli beta-galactosidase (lacZ).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
DI   NCIt; C27677; Human papillomavirus-related endocervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_E8AP ! HeLa-LTR-lacZ clone Z24
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 10-04-25; Last updated: 10-04-25; Version: 1
//
RX   PubMed=1560526; DOI=10.1128/JVI.66.5.2814-2820.1992; PMCID=PMC241038;
RA   Charneau P., Alizon M., Clavel F.;
RT   "A second origin of DNA plus-strand synthesis is required for optimal
RT   human immunodeficiency virus replication.";
RL   J. Virol. 66:2814-2820(1992).
//