Cellosaurus MAGIC-5 (CVCL_E8AM)
| Cell line name | MAGIC-5 |
|---|---|
| Synonyms | MAGIC-5A 1-10; HeLa/CD4+ cell clone 1-10 |
| Accession | CVCL_E8AM |
| Resource Identification Initiative | To cite this cell line use: MAGIC-5 (RRID:CVCL_E8AM) |
| Comments | Population: African American. Characteristics: Transfected with a construct pJK2 containing the HIV-1 LTR fused to a lacZ reporter gene that contains a MPKKKRK N-terminal sequence directing it to the nucleus (from parent cell line). Genetic integration: Method=Transduction; Gene=HGNC; HGNC:1678; CD4. Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo. Genetic integration: Method=Transfection; Gene=HGNC; HGNC:1606; CCR5. Genetic integration: Method=Transfection; Gene=UniProtKB; P00722; Escherichia coli beta-galactosidase (lacZ). Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR). Genetic integration: Method=Transfection; Gene=UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR). Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18). Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002. |
| Disease | Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677) |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_D259 (HeLa-MAGI) |
| Sex of cell | Female |
| Age at sampling | 30Y6M |
| Category | Cancer cell line |
| Publications | PubMed=11158746; DOI=10.1128/AAC.45.2.495-501.2001; PMCID=PMC90318 |
| Entry history | |
| Entry creation | 10-Apr-2025 |
| Last entry update | 14-Aug-2025 |
| Version number | 2 |