ID   MAGIC-5
AC   CVCL_E8AM
SY   MAGIC-5A 1-10; HeLa/CD4+ cell clone 1-10
RX   PubMed=11158746;
CC   Population: African American.
CC   Characteristics: Transfected with a construct pJK2 containing the HIV-1 LTR fused to a lacZ reporter gene that contains a MPKKKRK N-terminal sequence directing it to the nucleus (from parent cell line).
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:1678; CD4.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:1606; CCR5.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00722; Escherichia coli beta-galactosidase (lacZ).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR).
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
DI   NCIt; C27677; Human papillomavirus-related endocervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_D259 ! HeLa-MAGI
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 10-04-25; Last updated: 10-04-25; Version: 1
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RX   PubMed=11158746; DOI=10.1128/AAC.45.2.495-501.2001; PMCID=PMC90318;
RA   Hachiya A., Aizawa-Matsuoka S., Tanaka M., Takahashi Y., Ida S.,
RA   Gatanaga H., Hirabayashi Y., Kojima A., Tatsumi M., Oka S.;
RT   "Rapid and simple phenotypic assay for drug susceptibility of human
RT   immunodeficiency virus type 1 using CCR5-expressing HeLa/CD4(+) cell
RT   clone 1-10 (MAGIC-5).";
RL   Antimicrob. Agents Chemother. 45:495-501(2001).
//