Cellosaurus KS1/4 (CVCL_E7ZR)
| Cell line name | KS1/4 |
|---|---|
| Accession | CVCL_E7ZR |
| Resource Identification Initiative | To cite this cell line use: KS1/4 (RRID:CVCL_E7ZR) |
| Comments | Biotechnology: The monoclonal antibody produced by this hybridoma was conjugated to to methotrexate (KS1/4-methotrexate) or vinblastine (KS1/4-DAVLB or LY256787) in phase 1 clinical studies in patients with non-small cell lung carcinoma. These studies were stopped because of human anti-murine antibody (HAMA) response. Monoclonal antibody isotype: IgG2a, kappa. Monoclonal antibody target: UniProtKB; P16422; Human EPCAM/CD326. |
| Species of origin | Mus musculus (Mouse) (NCBI Taxonomy: 10090) |
| Hierarchy | Parent: CVCL_3411 (P3X63Ag8) |
| Category | Hybridoma |
| Publications | PubMed=6362852 PubMed=2469722; DOI=10.4049/jimmunol.142.10.3662 |
| Cross-references | |
| Biological sample resources | ABCD; ABCD_BE890 |
| Entry history | |
| Entry creation | 10-Apr-2025 |
| Last entry update | 10-Apr-2025 |
| Version number | 1 |