ID   KS1/4
AC   CVCL_E7ZR
DR   ABCD; ABCD_BE890
RX   PubMed=2469722;
RX   PubMed=6362852;
CC   Biotechnology: The monoclonal antibody produced by this hybridoma was conjugated to to methotrexate (KS1/4-methotrexate) or vinblastine (KS1/4-DAVLB or LY256787) in phase 1 clinical studies in patients with non-small cell lung carcinoma. These studies were stopped because of human anti-murine antibody (HAMA) response.
CC   Monoclonal antibody isotype: IgG2a, kappa.
CC   Monoclonal antibody target: UniProtKB; P16422; Human EPCAM/CD326.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_3411 ! P3X63Ag8
CA   Hybridoma
DT   Created: 10-04-25; Last updated: 10-04-25; Version: 1
//
RX   PubMed=2469722; DOI=10.4049/jimmunol.142.10.3662;
RA   Perez M.S., Walker L.E.;
RT   "Isolation and characterization of a cDNA encoding the KS1/4
RT   epithelial carcinoma marker.";
RL   J. Immunol. 142:3662-3667(1989).
//
RX   PubMed=6362852;
RA   Varki N.M., Reisfeld R.A., Walker L.E.;
RT   "Antigens associated with a human lung adenocarcinoma defined by
RT   monoclonal antibodies.";
RL   Cancer Res. 44:681-687(1984).
//