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Cellosaurus K1735-C4.S2-3 (CVCL_E7ZJ)

[Text version]
Cell line name K1735-C4.S2-3
Synonyms C4.S2.3
Accession CVCL_E7ZJ
Resource Identification Initiative To cite this cell line use: K1735-C4.S2-3 (RRID:CVCL_E7ZJ)
Comments Genetic integration: Method=Transfection; Gene=MGI; MGI:97361; Nos2 (Note=With p.Ser1113_Leu1144 replaced with ASVLLNPQNN; inactive).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Transformant: NCIt; C17231; Ultraviolet radiation.
Sequence variations
  • Mutation; MGI; MGI:97376; Nras; Simple; p.Gly13Asp (c.38G>A); Zygosity=Unspecified (from parent cell line).
Disease Mouse melanoma (NCIt: C21790)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C3H/HeN.
Hierarchy Parent: CVCL_E7ZF (K1735-C4)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=7535333; DOI=10.1084/jem.181.4.1333; PMCID=PMC2191958
Ke-Ping Xie, Su-Yun Huang, Zhong-Yun Dong, Shin-Hun Juang, Mordechai Gutman, Qiao-Wen Xie, Carl F. Nathan, Isaiah Joshua Fidler;
Transfection with the inducible nitric oxide synthase gene suppresses tumorigenicity and abrogates metastasis by K-1735 murine melanoma cells.
J. Exp. Med. 181:1333-1343(1995)

Entry history
Entry creation10-Apr-2025
Last entry update14-Aug-2025
Version number2