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Cellosaurus K1735-C4.L8.5 (CVCL_E7ZI)

[Text version]
Cell line name K1735-C4.L8.5
Synonyms C4.L8.5
Accession CVCL_E7ZI
Resource Identification Initiative To cite this cell line use: K1735-C4.L8.5 (RRID:CVCL_E7ZI)
Comments Genetic integration: Method=Transfection; Gene=MGI; MGI:97361; Nos2.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCIt; C17231; Ultraviolet radiation.
Sequence variations
  • Mutation; MGI; MGI:97376; Nras; Simple; p.Gly13Asp (c.38G>A); Zygosity=Unspecified (from parent cell line).
Disease Mouse melanoma (NCIt: C21790)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C3H/HeN.
Hierarchy Parent: CVCL_E7ZF (K1735-C4)
Category Cancer cell line
Publications

PubMed=7535333; DOI=10.1084/jem.181.4.1333; PMCID=PMC2191958
Xie K.-P., Huang S.-Y., Dong Z.-Y., Juang S.-H., Gutman M., Xie Q.-W., Nathan C.F., Fidler I.J.
Transfection with the inducible nitric oxide synthase gene suppresses tumorigenicity and abrogates metastasis by K-1735 murine melanoma cells.
J. Exp. Med. 181:1333-1343(1995)

Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1