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Cellosaurus MDCK II CLDN2 KO4 (CVCL_E7Z6)

[Text version]
Cell line name MDCK II CLDN2 KO4
Synonyms MDCK II claudin-2 knockout clone 4
Accession CVCL_E7Z6
Resource Identification Initiative To cite this cell line use: MDCK II CLDN2 KO4 (RRID:CVCL_E7Z6)
Comments Knockout cell: Method=TALEN; VGNC; VGNC:39316; CLDN2.
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Cell type: Epithelial cell of kidney; CL=CL_0002518.
Species of origin Canis lupus familiaris (Dog) (Canis familiaris) (NCBI Taxonomy: 9615)
Breed/subspecies: Cocker Spaniel; VBO=VBO_0200372.
Hierarchy Parent: CVCL_0424 (MDCK-II)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=25781928; DOI=10.1371/journal.pone.0119869; PMCID=PMC4363821
Tokuda S., Furuse M.
Claudin-2 knockout by TALEN-mediated gene targeting in MDCK cells: claudin-2 independently determines the leaky property of tight junctions in MDCK cells.
PLoS ONE 10:e0119869.1-e0119869.22(2015)

Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1