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Cellosaurus ARCaPE-shEPLIN (CVCL_E7VL)

[Text version]
Cell line name ARCaPE-shEPLIN
Synonyms ARCaPE-shRNA clone #102)
Accession CVCL_E7VL
Resource Identification Initiative To cite this cell line use: ARCaPE-shEPLIN (RRID:CVCL_E7VL)
Comments Population: Caucasian.
Knockout cell: Method=shRNA knockdown; HGNC; HGNC:24636; LIMA1.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg196Ter (c.586C>T); ClinVar=VCV000043589; Zygosity=Unspecified (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_E7VJ (ARCaPE)
Sex of cell Male
Age at sampling 83Y
Category Cancer cell line
Web pages Provider; Emory OTT; RT006; https://emoryott.technologypublisher.com/techcase/RT006
Publications

PubMed=21625216; DOI=10.1038/onc.2011.199; PMCID=PMC3165108
Zhang S.-M., Wang X., Osunkoya A.O., Iqbal S.A., Wang Y., Chen Z., Muller S., Chen Z.-J., Josson S., Coleman I.M., Nelson P.S., Wang Y.-Q.A., Wang R.-X., Shin D.M., Marshall F.F., Kucuk O., Chung L.W.K., Zhau H.-Y.E., Wu D.-Q.
EPLIN downregulation promotes epithelial-mesenchymal transition in prostate cancer cells and correlates with clinical lymph node metastasis.
Oncogene 30:4941-4952(2011)

Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1