Cellosaurus cell line B6BC CL (CVCL

Cellosaurus B6BC CL (CVCL_E7HN)

Entry history
Cell line name	B6BC CL
Synonyms	B6BC
Accession	CVCL_E7HN
Resource Identification Initiative	To cite this cell line use: B6BC CL (RRID:CVCL_E7HN)
Comments	Characteristics: Hormone receptor-positive. Tumorigenic. Will induce tumors when injected subcutaneously in the mammary fat pad of immunocompetent tumor-naive C57BL/6 mice (PubMed=37344100). Transformant: ChEBI; CHEBI_6716; Medroxyprogesterone acetate (MPA). Transformant: ChEBI; CHEBI_254496; 7,12-dimethyltetraphene (DMBA; dimethylbenzanthracene). Derived from site: In situ; Mammary gland; UBERON=UBERON_0001911.
Disease	Malignant neoplasms of the mouse mammary gland (NCIt: C21678)
Species of origin	Mus musculus (Mouse) (NCBI Taxonomy: 10090) Breed/subspecies: C57BL/6.
Originate from same individual	CVCL_E7HU ! B7BC CL
Sex of cell	Female
Age at sampling	13-16W
Category	Cancer cell line
Web pages	Provider; Inserm Transfert; RT00656; https://technology-offers.inserm-transfert.com/offer/b6bc-cell-line/
Publications	PubMed=37344100; DOI=10.1136/jitc-2023-007117; PMCID=PMC10314679 Perez-Lanzon M., Carbonnier V., Cordier P., De Palma F.D.E., Petrazzuolo A., Klein C., Arbaretaz F., Mangane K., Stoll G., Martins I., Fohrer-Ting H., Paillet J., Mouillet-Richard S., Le Corre D., Xiao W.-J., Sroussi M., Desdouets C., Laurent-Puig P., Pol J.G., Lopez-Otin C., Maiuri M.C., Kroemer G. New hormone receptor-positive breast cancer mouse cell line mimicking the immune microenvironment of anti-PD-1 resistant mammary carcinoma. J. Immunother. Cancer 11:e007117.1-e007117.17(2023)
Entry creation	10-Apr-2025
Last entry update	10-Apr-2025
Version number	1