ID   B6BC CL
AC   CVCL_E7HN
SY   B6BC
RX   PubMed=37344100;
WW   Provider; Inserm Transfert; RT00656; https://technology-offers.inserm-transfert.com/offer/b6bc-cell-line/
CC   Characteristics: Hormone receptor-positive. Tumorigenic. Will induce tumors when injected subcutaneously in the mammary fat pad of immunocompetent tumor-naive C57BL/6 mice (PubMed=37344100).
CC   Transformant: ChEBI; CHEBI_6716; Medroxyprogesterone acetate (MPA).
CC   Transformant: ChEBI; CHEBI_254496; 7,12-dimethyltetraphene (DMBA; dimethylbenzanthracene).
CC   Derived from site: In situ; Mammary gland; UBERON=UBERON_0001911.
CC   Breed/subspecies: C57BL/6.
DI   NCIt; C21678; Malignant neoplasms of the mouse mammary gland
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
OI   CVCL_E7HU ! B7BC CL
SX   Female
AG   13-16W
CA   Cancer cell line
DT   Created: 10-04-25; Last updated: 10-04-25; Version: 1
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RX   PubMed=37344100; DOI=10.1136/jitc-2023-007117; PMCID=PMC10314679;
RA   Perez-Lanzon M., Carbonnier V., Cordier P., De Palma F.D.E.,
RA   Petrazzuolo A., Klein C., Arbaretaz F., Mangane K., Stoll G., Martins I.,
RA   Fohrer-Ting H., Paillet J., Mouillet-Richard S., Le Corre D., Xiao W.-J.,
RA   Sroussi M., Desdouets C., Laurent-Puig P., Pol J.G., Lopez-Otin C.,
RA   Maiuri M.C., Kroemer G.;
RT   "New hormone receptor-positive breast cancer mouse cell line mimicking
RT   the immune microenvironment of anti-PD-1 resistant mammary carcinoma.";
RL   J. Immunother. Cancer 11:e007117.1-e007117.17(2023).
//