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Cellosaurus JEI-002 (CVCL_E7HB)

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Cell line name JEI-002
Synonyms Jiaotong Ear Institute-002
Accession CVCL_E7HB
Resource Identification Initiative To cite this cell line use: JEI-002 (RRID:CVCL_E7HB)
Comments Group: Patented cell line.
Population: Chinese.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Peripheral nervous system, vestibular nerve; UBERON=UBERON_0003723.
Cell type: Schwann cell; CL=CL_0002573.
Sequence variations
  • Mutation; HGNC; HGNC:7773; NF2; Simple; p.Lys80Lys (c.240G>A); ClinVar=VCV000451710; Zygosity=Heterozygous; Note=Has an effect on splicing (PubMed=35359340).
Disease Vestibular schwannoma (NCIt: C3276)
Vestibular schwannoma (ORDO: Orphanet_252175)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 44Y
Category Transformed cell line
STR profile Source(s): PubMed=35359340

Markers:
AmelogeninX
CSF1PO10
D2S133818,25
D3S135815,18
D5S81811,13
D6S104311,22
D7S82010,11
D8S117913,16
D12S39119,21
D13S3178,13
D16S53911,13
D18S5113,18
D19S43313.2,14
D21S1130,32.2
FGA23,24
Penta D9,12
Penta E14,21
TH017,9.3
TPOX8,12
vWA16,18

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Publications

Patent=CN114807043A
Hao Wu, Zhao-Yan Wang, Lu Xue, Wei-Wei He, Wen-Ying Shu, Yao-Xuan Wang;
Human-derived vestibular schwannoma immortalized cell line and construction method thereof.
Patent number CN114807043A, 29-Jul-2022

PubMed=35359340; DOI=10.1155/2022/7507857; PMCID=PMC8961447
Wei-Wei He, Wen-Ying Shu, Lu Xue, Yao-Xuan Wang, Yong-Chuan Chai, Hao Wu, Zhao-Yan Wang;
Synergistic effect of erastin combined with nutlin-3 on vestibular schwannoma cells as p53 modulates erastin-induced ferroptosis response.
J. Oncol. 2022:7507857.1-7507857.18(2022)

Entry history
Entry creation10-Apr-2025
Last entry update14-Aug-2025
Version number2