ID   JEI-002
AC   CVCL_E7HB
SY   Jiaotong Ear Institute-002
RX   Patent=CN114807043A;
RX   PubMed=35359340;
CC   Group: Patented cell line.
CC   Population: Chinese.
CC   Sequence variation: Mutation; HGNC; HGNC:7773; NF2; Simple; p.Lys80Lys (c.240G>A); ClinVar=VCV000451710; Zygosity=Heterozygous; Note=Has an effect on splicing (PubMed=35359340).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; SV40 large T antigen.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Derived from site: In situ; Peripheral nervous system, vestibular nerve; UBERON=UBERON_0003723.
CC   Cell type: Schwann cell; CL=CL_0002573.
ST   Source(s): PubMed=35359340
ST   Amelogenin: X
ST   CSF1PO: 10
ST   D12S391: 19,21
ST   D13S317: 8,13
ST   D16S539: 11,13
ST   D18S51: 13,18
ST   D19S433: 13.2,14
ST   D21S11: 30,32.2
ST   D2S1338: 18,25
ST   D3S1358: 15,18
ST   D5S818: 11,13
ST   D6S1043: 11,22
ST   D7S820: 10,11
ST   D8S1179: 13,16
ST   FGA: 23,24
ST   Penta D: 9,12
ST   Penta E: 14,21
ST   TH01: 7,9.3
ST   TPOX: 8,12
ST   vWA: 16,18
DI   NCIt; C3276; Vestibular schwannoma
DI   ORDO; Orphanet_252175; Vestibular schwannoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   44Y
CA   Transformed cell line
DT   Created: 10-04-25; Last updated: 10-04-25; Version: 1
//
RX   Patent=CN114807043A;
RA   Wu H., Wang Z.-Y., Xue L., He W.-W., Shu W.-Y., Wang Y.-X.;
RT   "Human-derived vestibular schwannoma immortalized cell line and
RT   construction method thereof.";
RL   Patent number CN114807043A, 29-Jul-2022.
//
RX   PubMed=35359340; DOI=10.1155/2022/7507857; PMCID=PMC8961447;
RA   He W.-W., Shu W.-Y., Xue L., Wang Y.-X., Chai Y.-C., Wu H.,
RA   Wang Z.-Y.;
RT   "Synergistic effect of erastin combined with nutlin-3 on vestibular
RT   schwannoma cells as p53 modulates erastin-induced ferroptosis
RT   response.";
RL   J. Oncol. 2022:7507857.1-7507857.18(2022).
//