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Cellosaurus cEND (CVCL_E7H9)

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Cell line name cEND
Accession CVCL_E7H9
Resource Identification Initiative To cite this cell line use: cEND (RRID:CVCL_E7H9)
Comments Characteristics: Provides a useful model for studies involving the differentiation and regulation of blood brain barrier as it shares principal features of the BBB in vivo (ABM=T0290).
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03077; Murine polyomavirus (strain A2) (MPyV) middle T antigen (PyMT).
Transformant: NCBI_TaxID; 10636; Murine polyomavirus (strain A2) (MPyV).
Derived from site: In situ; Brain, cerebral cortex; UBERON=UBERON_0000956.
Cell type: Brain microvascular endothelial cell; CL=CL_2000044.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Sex of cell Sex unspecified
Age at sampling 3-5D
Category Transformed cell line
Publications

PubMed=22951995; DOI=10.3791/4022; PMCID=PMC3486758
Malgorzata Burek, Ellaine Salvador, Carola Y. Forster;
Generation of an immortalized murine brain microvascular endothelial cell line as an in vitro blood brain barrier model.
J. Vis. Exp. 66:e4022.1-e4022.6(2012)

Cross-references
Cell line collections (Providers) ABM; T0290
Entry history
Entry creation10-Apr-2025
Last entry update14-Aug-2025
Version number2