ID   cEND
AC   CVCL_E7H9
DR   ABM; T0290
RX   PubMed=22951995;
CC   Characteristics: Provides a useful model for studies involving the differentiation and regulation of blood brain barrier as it shares principal features of the BBB in vivo (ABM=T0290).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03077; Murine polyomavirus (strain A2) (MPyV) middle T antigen (PyMT).
CC   Transformant: NCBI_TaxID; 10636; Murine polyomavirus (strain A2) (MPyV).
CC   Derived from site: In situ; Brain, cerebral cortex; UBERON=UBERON_0000956.
CC   Cell type: Brain microvascular endothelial cell; CL=CL_2000044.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Sex unspecified
AG   3-5D
CA   Transformed cell line
DT   Created: 10-04-25; Last updated: 14-08-25; Version: 2
//
RX   PubMed=22951995; DOI=10.3791/4022; PMCID=PMC3486758;
RA   Burek, Malgorzata
RA   Salvador, Ellaine
RA   Forster, Carola Y.
RT   "Generation of an immortalized murine brain microvascular endothelial
RT   cell line as an in vitro blood brain barrier model.";
RL   J. Vis. Exp. 66:e4022.1-e4022.6(2012).
//