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Cellosaurus MTC (CVCL_E7H6)

[Text version]
Cell line name MTC
Accession CVCL_E7H6
Resource Identification Initiative To cite this cell line use: MTC (RRID:CVCL_E7H6)
Comments Characteristics: Established from a rat implanted with the DMBA-induced rat mammary adenocarcinoma 13762NF (PubMed=6950180).
Doubling time: 13.5 hours (PubMed=6950180).
Transformant: ChEBI; CHEBI_254496; 7,12-dimethyltetraphene (DMBA; dimethylbenzanthracene).
Derived from site: In situ; Mammary gland; UBERON=UBERON_0001911.
Disease Adenocarcinoma of the rat mammary gland (NCIt: C64011)
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Fischer 344; RS=RS_0000215.
Originate from same individual CVCL_8133 ! MTLn2
CVCL_8136 ! MTLn3
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=6950180; DOI=10.1093/jnci/68.3.507
Anthony Neri, Dan Welch, Takanori Kawaguchi, Garth L. Nicolson;
Development and biologic properties of malignant cell sublines and clones of a spontaneously metastasizing rat mammary adenocarcinoma.
J. Natl. Cancer Inst. 68:507-517(1982)

PubMed=8521618; DOI=10.1007/BF00157687
Jeffrey E. Segall, Sangeeta K. Tyerech, Lucia R. Boselli, Susan Masseling, Joseph Benjamin Helft, Amanda Chan, Joan Jones, John Stephen Condeelis;
EGF stimulates lamellipod extension in metastatic mammary adenocarcinoma cells by an actin-dependent mechanism.
Clin. Exp. Metastasis 14:61-72(1996)

PubMed=21104427; DOI=10.1007/s10585-010-9362-8
Mustafa K. Dabbous, M. Margaret Jefferson, Lena Haney, Edwin L. Thomas;
Biomarkers of metastatic potential in cultured adenocarcinoma clones.
Clin. Exp. Metastasis 28:101-111(2011)

Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1