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Cellosaurus RMF/EG (CVCL_E7G3)

[Text version]
Cell line name RMF/EG
Synonyms Reduction Mammary Fibroblasts immortalized with human Telomere and GFP
Accession CVCL_E7G3
Resource Identification Initiative To cite this cell line use: RMF/EG (RRID:CVCL_E7G3)
Comments Characteristics: Used humanize the fat pad of NOD/SCID mice prior to engrafting patient samples to generate PDX models (PubMed=15051869).
Genetic integration: Method=Transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:4893; HGF.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11766; TGFB1.
Genetic integration: Method=Transduction; Gene=UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR).
Derived from site: In situ; Breast; UBERON=UBERON_0000310.
Cell type: Fibroblast of breast; CL=CL_4006000.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 29-37Y
Category Telomerase immortalized cell line
Publications

PubMed=15051869; DOI=10.1073/pnas.0401064101; PMCID=PMC387357
Charlotte Kuperwasser, Tony Chavarria, Min Wu, Gregg G. Magrane, Joe W. Gray, Loucinda Carey, Andrea L. Richardson, Robert Allan Weinberg;
Reconstruction of functionally normal and malignant human breast tissues in mice.
Proc. Natl. Acad. Sci. U.S.A. 101:4966-4971(2004)

Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1