ID   RMF/EG
AC   CVCL_E7G3
SY   Reduction Mammary Fibroblasts immortalized with human Telomere and GFP
RX   PubMed=15051869;
CC   Characteristics: Used humanize the fat pad of NOD/SCID mice prior to engrafting patient samples to generate PDX models (PubMed=15051869).
CC   Genetic integration: Method=Transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:4893; HGF.
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11766; TGFB1.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR).
CC   Derived from site: In situ; Breast; UBERON=UBERON_0000310.
CC   Cell type: Fibroblast of breast; CL=CL_4006000.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   29-37Y
CA   Telomerase immortalized cell line
DT   Created: 10-04-25; Last updated: 10-04-25; Version: 1
//
RX   PubMed=15051869; DOI=10.1073/pnas.0401064101; PMCID=PMC387357;
RA   Kuperwasser, Charlotte
RA   Chavarria, Tony
RA   Wu, Min
RA   Magrane, Gregg G.
RA   Gray, Joe W.
RA   Carey, Loucinda
RA   Richardson, Andrea L.
RA   Weinberg, Robert Allan
RT   "Reconstruction of functionally normal and malignant human breast
RT   tissues in mice.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:4966-4971(2004).
//