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Cellosaurus BFH12 CYP3A74 KO (CVCL_E7BR)

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Cell line name BFH12 CYP3A74 KO
Accession CVCL_E7BR
Resource Identification Initiative To cite this cell line use: BFH12 CYP3A74 KO (RRID:CVCL_E7BR)
Comments Knockout cell: Method=CRISPR/Cas9; VGNC; VGNC:110267; CYP3A74.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pRetro-E2 SV40).
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Fetal liver; UBERON=UBERON_0002107.
Cell type: Hepatocyte; CL=CL_0000182.
Species of origin Bos taurus (Bovine) (NCBI Taxonomy: 9913)
Breed/subspecies: Holstein Friesian; VBO=VBO_0003171.
Hierarchy Parent: CVCL_JQ51 (BFH12)
Sex of cell Sex unspecified
Age at sampling Fetus
Category Finite cell line
Publications

PubMed=38648904; DOI=10.1016/j.bcp.2024.116231
Silvia Iori, Caterina D'Onofrio, Nihay Laham-Karam, Isidore Mushimiyimana, Lorena Lucatello, Ludovica Montanucci, Rosa Maria Lopparelli, Federico Bonsembiante, Francesca Capolongo, Marianna Pauletto, Mauro Dacasto, Mery Giantin;
Generation and characterization of cytochrome P450 3A74 CRISPR/Cas9 knockout bovine foetal hepatocyte cell line (BFH12).
Biochem. Pharmacol. 224:116231.1-116231.11(2024)

Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1