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Cellosaurus U2OS-BP6#48 (CVCL_E6ZW)

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Cell line name U2OS-BP6#48
Synonyms U2OS-BP6 clone 48
Accession CVCL_E6ZW
Resource Identification Initiative To cite this cell line use: U2OS-BP6#48 (RRID:CVCL_E6ZW)
Comments Population: Caucasian.
Virology: The parent cell line which contains chromosomally integrated human herpesvirus 6B (ciHHV-6B) was surinfected with HHV-6A. The resulting cell line contains an average of 0.6 HHV-6A and 0.6 HHV-6B genomes/cell (PubMed=28468878).
Derived from site: In situ; Bone, tibia; UBERON=UBERON_0000979.
Sequence variations
  • Mutation; HGNC; HGNC:9277; PPM1D; Simple; p.Arg458Ter (c.1372C>T); ClinVar=VCV002445214; Zygosity=Heterozygous (from parent cell line).
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_E6ZV (U2OS-BP6)
Sex of cell Female
Age at sampling 15Y
Category Cancer cell line
Publications

PubMed=28468878; DOI=10.1128/JVI.00437-17; PMCID=PMC5487542
Annie Gravel, Isabelle Dubuc, Nina Wallaschek, Shella Gilbert-Girard, Vanessa Collin, Ruth Hall-Sedlak, Keith R. Jerome, Yasuko Mori, Julie Carbonneau, Guy Boivin, Benedikt B. Kaufer, Louis Flamand;
Cell culture systems to study human herpesvirus 6A/B chromosomal integration.
J. Virol. 91:e00437.17.1-e00437.17.14(2017)

Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1