ID   U2OS-BP6#48
AC   CVCL_E6ZW
SY   U2OS-BP6 clone 48
RX   PubMed=28468878;
CC   Population: Caucasian.
CC   Virology: The parent cell line which contains chromosomally integrated human herpesvirus 6B (ciHHV-6B) was surinfected with HHV-6A. The resulting cell line contains an average of 0.6 HHV-6A and 0.6 HHV-6B genomes/cell (PubMed=28468878).
CC   Sequence variation: Mutation; HGNC; HGNC:9277; PPM1D; Simple; p.Arg458Ter (c.1372C>T); ClinVar=VCV002445214; Zygosity=Heterozygous (from parent cell line).
CC   Derived from site: In situ; Bone, tibia; UBERON=UBERON_0000979.
DI   NCIt; C9145; Osteosarcoma
DI   ORDO; Orphanet_668; Osteosarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_E6ZV ! U2OS-BP6
SX   Female
AG   15Y
CA   Cancer cell line
DT   Created: 10-04-25; Last updated: 10-04-25; Version: 1
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RX   PubMed=28468878; DOI=10.1128/JVI.00437-17; PMCID=PMC5487542;
RA   Gravel A., Dubuc I., Wallaschek N., Gilbert-Girard S., Collin V.,
RA   Hall-Sedlak R., Jerome K.R., Mori Y., Carbonneau J., Boivin G.,
RA   Kaufer B.B., Flamand L.;
RT   "Cell culture systems to study human herpesvirus 6A/B chromosomal
RT   integration.";
RL   J. Virol. 91:e00437.17.1-e00437.17.14(2017).
//