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Cellosaurus AsPC1/Luciferase-2A-GFP (CVCL_E6XP)

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Cell line name AsPC1/Luciferase-2A-GFP
Synonyms AsPC1 / Luciferase & GFP
Accession CVCL_E6XP
Resource Identification Initiative To cite this cell line use: AsPC1/Luciferase-2A-GFP (RRID:CVCL_E6XP)
Comments Population: Caucasian.
Characteristics: Transduced by lentivirus with a EF1a-Luc-2A-eGFP-Rsv-PuroR construct (GenTarget=SC062-LG).
Genetic integration: Method=Transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations
  • Gene deletion; HGNC; HGNC:6844; MAP2K4; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Leu78Hisfs*41 (c.233_234delTC) (p.His93Profs*67, c.276_277delTC); ClinVar=VCV000977782; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6770; SMAD4; Simple; p.Arg100Thr (c.299G>C); Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Cys135Alafs*35 (c.403delT); ClinVar=VCV001069265; Zygosity=Heterozygous (from parent cell line).
Disease Pancreatic ductal adenocarcinoma (NCIt: C9120)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0152 (AsPC-1)
Sex of cell Female
Age at sampling 62Y
Category Cancer cell line
Web pages Provider; GenTarget; SC062-LG; https://www.gentarget.com/product/human-aspc1-luciferase-gfp-stable-cells/
Entry history
Entry creation10-Apr-2025
Last entry update14-Aug-2025
Version number2