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Cellosaurus HUES6 SOX11 ES.HET2 (CVCL_E6ID)

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Cell line name HUES6 SOX11 ES.HET2
Synonyms ES.HET2
Accession CVCL_E6ID
Resource Identification Initiative To cite this cell line use: HUES6 SOX11 ES.HET2 (RRID:CVCL_E6ID)
Comments Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:11191; SOX11 (Note=1 of 2 alleles).
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Disease Coffin-Siris syndrome (NCIt: C35321)
Coffin-Siris syndrome (ORDO: Orphanet_1465)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_B194 (HUES 6)
Sex of cell Female
Age at sampling Blastocyst stage
Category Embryonic stem cell
Publications

PubMed=31035284; DOI=10.1093/hmg/ddz089
Soeren Turan, Tom Boerstler, Atria Kavyanifar, Sandra Loskarn, Andre Reis, Beate Winner, Dieter Chi-Chung Lie;
A novel human stem cell model for Coffin-Siris syndrome-like syndrome reveals the importance of SOX11 dosage for neuronal differentiation and survival.
Hum. Mol. Genet. 28:2589-2599(2019)

Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1