Cellosaurus IEC-Mx2Luc-10 (CVCL_E6EK)
| Cell line name | IEC-Mx2Luc-10 |
|---|---|
| Accession | CVCL_E6EK |
| Resource Identification Initiative | To cite this cell line use: IEC-Mx2Luc-10 (RRID:CVCL_E6EK) |
| Comments | Characteristics: Developed from a transgenic mouse that expresses luciferase driven by the promoter of the interferon-stimulated gene Mx2. Tool for the detection of type I and type III IFN responses that recapitulate the in vivo situation and to study the molecular mechanisms of innate immunity of the small intestinal epithelium (PubMed=23940817). Genetic integration: Method=Transduction; Gene=HGNC; HGNC:5362; ID3. Genetic integration: Method=Transduction; Gene=HGNC; HGNC:6348; KLF4. Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen. Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase. Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40). Derived from site: In situ; Fetal small intestine; UBERON=UBERON_0002108. Cell type: Epithelial cell of intestine; CL=CL_0002563. |
| Species of origin | Mus musculus (Mouse)
(NCBI Taxonomy: 10090)
Breed/subspecies: Mx2-Luc transgenic. |
| Sex of cell | Sex unspecified |
| Age at sampling | 19-20FD |
| Category | Transformed cell line |
| Publications | PubMed=23940817; DOI=10.1371/journal.pone.0072700; PMCID=PMC3734307 |
| Entry history | |
| Entry creation | 10-Apr-2025 |
| Last entry update | 14-Aug-2025 |
| Version number | 2 |