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Cellosaurus NIH 3T3 EGFR-V769_D770insASV (CVCL_E6DX)

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Cell line name NIH 3T3 EGFR-V769_D770insASV
Synonyms NIH/3T3 EGFR-V769_D770insASV
Accession CVCL_E6DX
Resource Identification Initiative To cite this cell line use: NIH 3T3 EGFR-V769_D770insASV (RRID:CVCL_E6DX)
Comments Genetic integration: Method=Transfection; Gene=HGNC; HGNC:3236; EGFR (Note=With p.Val769insAlaSerVal (c.2308_2309insCCAGCGTGG)).
Genetic integration: Method=Transfection; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Derived from site: In situ; Whole embryo; UBERON=UBERON_0000922.
Cell type: Fibroblast; CL=CL_0000057.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: NIH Swiss.
Hierarchy Parent: CVCL_0594 (NIH 3T3)
Sex of cell Male
Age at sampling Embryo
Category Spontaneously immortalized cell line
Publications

PubMed=29748209; DOI=10.1158/1535-7163.MCT-17-1206
Hasako S., Terasaka M., Abe N., Uno T., Ohsawa H., Hashimoto A., Fujita R., Tanaka K., Okayama T., Wadhwa R., Miyadera K., Aoyagi Y., Yonekura K., Matsuo K.
TAS6417, a novel EGFR inhibitor targeting exon 20 insertion mutations.
Mol. Cancer Ther. 17:1648-1658(2018)

Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1