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Cellosaurus NIH 3T3 EGFR-A763_Y764insFQEA (CVCL_E6DQ)

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Cell line name NIH 3T3 EGFR-A763_Y764insFQEA
Synonyms NIH/3T3 EGFR-A763_Y764insFQEA
Accession CVCL_E6DQ
Resource Identification Initiative To cite this cell line use: NIH 3T3 EGFR-A763_Y764insFQEA (RRID:CVCL_E6DQ)
Comments Genetic integration: Method=Transfection; Gene=HGNC; HGNC:3236; EGFR (Note=With p.Ala763insPheGlnGluAla (c.2290_2291insTCCAGGAAGCCT)).
Genetic integration: Method=Transfection; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: In situ; Whole embryo; UBERON=UBERON_0000922.
Cell type: Fibroblast; CL=CL_0000057.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: NIH Swiss.
Hierarchy Parent: CVCL_0594 (NIH 3T3)
Sex of cell Male
Age at sampling Embryo
Category Spontaneously immortalized cell line
Publications

PubMed=29748209; DOI=10.1158/1535-7163.MCT-17-1206
Shinichi Hasako, Miki Terasaka, Naomi Abe, Takao Uno, Hirokazu Ohsawa, Akihiro Hashimoto, Ryoto Fujita, Kenji Tanaka, Takashige Okayama, Renu Wadhwa, Kazutaka Miyadera ...Show all 14 authors... , Yoshimi Aoyagi, Kazuhiko Yonekura, Kenichi Matsuo; Show fewer authors
TAS6417, a novel EGFR inhibitor targeting exon 20 insertion mutations.
Mol. Cancer Ther. 17:1648-1658(2018)

Entry history
Entry creation10-Apr-2025
Last entry update14-Aug-2025
Version number2